Meloxicam is a prescription drug that can treat pain and inflammation caused by arthritis. However, it can also cause serious side effects that may affect your heart, stomach, liver, kidneys, or skin. Some of these side effects are:

• Cardiovascular events: Meloxicam can increase your risk of heart attack, stroke, blood clots, and heart failure. These events can be fatal and occur without warning. Seek emergency help if you have chest pain, shortness of breath, weakness, slurred speech, or vision problems. ^{1 2}

• Gastrointestinal bleeding: Meloxicam can cause ulcers, perforations, or bleeding in your stomach or intestines. These conditions can be fatal and occur without warning. Call your doctor right away if you have black, bloody, or tarry stools, or vomit blood or something that looks like coffee grounds. ^{1 2}

• Liver damage: Meloxicam can cause liver problems, such as hepatitis, jaundice, or liver failure. These problems can be fatal and occur at any time. Stop taking meloxicam and contact your doctor immediately if you have signs of liver damage, such as nausea, fatigue, loss of appetite, dark urine, or yellowing of your skin or eyes. ^{1 2}

• Kidney damage: Meloxicam can cause kidney problems, such as acute kidney injury, nephrotic syndrome, or kidney failure. These problems can be fatal and occur at any time. Tell your doctor if you have signs of kidney damage such as changes in urination, swelling, or blood in your urine. ^{1 2}

• Skin reactions: Meloxicam can cause severe allergic reactions, such as anaphylaxis, angioedema, or Stevens-Johnson syndrome. These reactions can be fatal and occur at any time. Stop taking meloxicam and get emergency help if you have symptoms such as rash, itching, swelling, trouble breathing, or fever. ^{1 2}