In addition to its intrinsic safety, buprenorphine's relatively low abuse liability in the combination product (i.e., with naloxone as Suboxone®) makes it even more acceptable in regulatory quarters as well as to prescribing physicians.
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A buprenorphine/naloxone formulation was developed to mitigate this misuse risk. This randomized, double-blind, cross-over study was conducted to assess the ...
Abuse liability of intravenous buprenorphine/naloxone and buprenorphine alone in buprenorphine-maintained intravenous heroin abusers. Addiction. 2010;105(4):709 ...
Both block the effects of opiates while reducing opiate cravings and easing withdrawal symptoms. Buprenorphine is the only opiate addiction therapy drug that ...
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Mar 28, 2024 · Common and Serious Side Effects of Buprenorphine · Respiratory distress · Overdose · Adrenal insufficiency · Dependence · Withdrawal · Itching, pain, ...
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Mar 26, 1981 · This study was designed to assess the dependence-producing capacity of the opiate partial agonist, buprenorphine.
The study is designed to compare the abuse liabilities of intravenous buprenorphine and buprenorphine/naloxone in individuals who are physically dependent on ...
Jan 2, 2018 · The partial agonistic property of buprenorphine reduces the likelihood and severity of overdose, and limits liability to physical dependence ( ...