Cadherin-1
Protein
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Cadherin-1 or Epithelial cadherin, is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. CDH1 has also been designated as CD324. It is a tumor suppressor... Wikipedia
Location (UCSC): Chr 16: 68.74 – 68.84 Mb
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May 27, 2024 · It is a tumor suppressor gene and can be used as a biomarker to assess and evaluate the progression and prognosis of oral dysplastic lesions and ...
Cadherin-1 or Epithelial cadherin (E-cadherin) is a protein that in humans is encoded by the CDH1 gene. Mutations are correlated with gastric, breast, ...
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Aug 1, 2017 · The CDH1 gene provides instructions for making a protein called epithelial cadherin or E-cadherin. This protein is found within the membrane ...
Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting ...
The human epithelial (E)-cadherin gene CDH1 maps to chromosome 16q22.1. Berx et al. [1] isolated the full-length gene by using recombinant lambda phage, cosmid ...
CDH1 (Cadherin 1) is a Protein Coding gene. Diseases associated with CDH1 include Diffuse Gastric And Lobular Breast Cancer Syndrome and Blepharocheilodontic ...
Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting ...
Oct 1, 2007 · It is a transmembrane glycoprotein with five extracellular domains that mediate intercellular adhesion through homophilic binding. The ...
Jun 5, 2021 · The E-Cadherin gene (CDH1, Cadherin 1), located at 16q22.1 encodes for a calcium-dependent membranous glycoprotein with an important role in ...
IMPORTANCE E-cadherin (CDH1) is a cancer predisposition gene mutated in families meeting clinically defined hereditary diffuse gastric cancer (HDGC). Reliable ...