Tarlatamab for Patients with Previously Treated Small-Cell Lung Cancer …
WEBOct 20, 2023 · Trial Design. DeLLphi-301 is a phase 2, open-label, international trial designed to evaluate the antitumor activity, safety, side-effect profile, and pharmacokinetics of tarlatamab in patients...
Small Cell Lung Cancer Clinical Trials - Mayo Clinic Research
WEBDisplaying 165 studies. Olaparib, Cediranib Maleate, and Standard Chemotherapy in Treating Patients With Small Cell Lung Cancer Jacksonville, FL. This randomized phase II trial studies how well olaparib, cediranib maleate, and standard chemotherapy work in treating patients with small cell lung cancer.
First-Line Atezolizumab plus Chemotherapy in Extensive-Stage Small-Cell …
WEBSep 25, 2018 · The IMpower133 trial evaluated the efficacy and safety of adding atezolizumab or placebo to first-line treatment with carboplatin and etoposide in patients with extensive-stage small-cell...
Targeted treatments for small-cell lung cancer
WEBApril 27, 2021. Targeted treatments for small-cell lung cancer. At a Glance. A rapid screening process identified a two-drug combination that shrank small-cell lung tumors, which are often fatal within weeks of recurrence.
A 2022 Update on Extensive Stage Small-Cell Lung Cancer (SCLC)
WEBJul 18, 2022 · In an open-label, 1:1 randomized, phase 3 French trial from 2020 with progression free survival (PFS) as the primary endpoint, 164 patients with histologically or cytologically confirmed advanced stage IV or locally relapsed small-cell lung cancer, who responded to first-line platinum plus etoposide treatment but relapsed or progressed ≥90 ...
Lurbinectedin as second-line treatment for patients with small-cell ...
WEBMar 27, 2020 · Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial. Summary. Background. Few options exist for treatment of patients with small-cell lung cancer (SCLC) after failure of first-line therapy. Lurbinectedin is a selective inhibitor of oncogenic transcription.
Lung Cancer - Small Cell: About Clinical Trials | Cancer.Net
WEBEvery drug that is now approved by the U.S. Food and Drug Administration (FDA) was tested in clinical trials. Clinical trials are used for all types and stages of SCLC. Many focus on new treatments to learn if a new treatment is safe, effective, and possibly better than the existing treatments.
Treatment Clinical Trials for Small Cell Lung Cancer - NCI
WEBClinical trials are research studies that involve people. The clinical trials on this list are for small cell lung cancer treatment. All trials on the list are NCI-supported clinical trials, which are sponsored or otherwise financially supported by NCI.
New approaches to small cell lung cancer therapy : from the …
WEBIn light of the limited durability of benefit from current therapies, it is of critical need to continue to explore new biomarker-directed therapeutic strategies and treatment combinations in the laboratory and in the clinic ( Figure 1 ).
Small-cell lung cancer | Nature Reviews Disease Primers
WEBArticle 12 August 2021. Introduction. Small-cell lung cancer (SCLC) is a high-grade neuroendocrine carcinoma arising predominantly in current or former smokers and has an exceptionally...
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